The Adaptive Network Fuzzy Inference System (ANFIS)-based Wireless Sensor Network (WSN) is designed to serve as a monitor of controller of an indoor air-conditioning system. The WSN comprises sensors to monitor the temperature of the indoor space and the ANFIS controller is used to control the fans in order to obtain energy-saving benefits. By using the Application Programming Interface (API) of WSNs, many applications have been developed. The experimental results demonstrate that good data transference and control performance have been achieved.