In the aeronautical current state of affairs, aerodynamic improvement in airfoil or in aircraft designs, including its configuration studies, remains to be the state-of-the-art research topics, which are being pursued by many aerodynamicists coming from high learning institutions, research agencies, or aircraft manufacturing industries. As part of the above general trends in aerodynamic activities, this current work has been dedicated to aerodynamic simulation studies of a wing-body configuration by using commercial software. The calculation has been conducted based on automatic unstructured hexahedral mesh generator and on the Reynolds-Averaged Navier-Stokes (RANS) principles.