The performance of application workloads is more critical to business success now than at any prior time in the history of IT. In the new hybrid enterprise era - in which mobility proliferates - data is generated in torrents, applications are increasingly virtualized and cloud computing is ascendant. Ensuring the performance of application workloads is a daunting challenge. How are organizations meeting the challenge? Astute prioritization, assessment and a robust application performance infrastructure are key requirements for success: prioritize the importance of application workloads, determine how best to run the workloads (physical or virtual) and where to run them (in the private or public cloud).