In this paper, the authors have considered a MC-CDMA where Inter-symbol interference is one of the biggest problems when the system is subjected in Awgn and Rayleigh Channel. Here, they have considered the efficient Transmitter and Receiver to reduce the inter-symbol Interference without considering the use of equalizer. When the number of users gets large, each user tends to choose more than one carrier, which do not suffer deep fading, while interference suppression is performed across the chosen carriers by the corresponding receiver. Results have shown that with efficient equalizer the inter-symbol interference can be reduced.