A happy personality having positive interpersonal relationships at work fosters a variety of beneficial outcomes for individuals and organizations. The present paper was designed to examine the effect of personality on happiness and interpersonal relationship of the employees. A total sample size of 93 was used in this study. The Eysenck Personality Inventory (EPI) was used to categorize personality of the employees. A comparative correlational design was used. The result of the present paper revealed that that there is a significant difference on happiness and interpersonal relationship-based on personality traits.