GPU-RMAP: Accelerating Short-Read Mapping on Graphics Processors
Next-generation, high-throughput sequencers are now capable of producing hundreds of billions of short sequences (reads) in a single day. The task of accurately mapping the reads back to a reference genome is of particular importance because it is used in several other biological applications, e.g., genome re-sequencing, DNA methylation, and ChiP sequencing. On a Personal Computer (PC), the computationally intensive short-read mapping task currently requires several hours to execute while working on very large sets of reads and genomes. Accelerating this task requires parallel computing.