Consideration of environmental and economic aspects in supply chain design is required to reduce negative impacts on the environment caused by the increasing levels of industrialization. In this paper, a new green supply chain design approach has been proposed to deal with the trade-offs between environmental and financial issues. The new approach incorporates a closed loop network to accommodate the reprocessing paradigm of disposal products and a multi-objective optimization mathematical model to minimize overall costs and carbon dioxide emissions when setting the supply chain network in which previous models in this type of network have not include environmental impact.