In Multi-User Multiple Input Multiple Output (MU-MIMO) system, the problem in transmission of data in downlink channel is that the particular signal is affected by other user signals. So, interference cancellation at Base Station (BS) is required. This paper is to eliminate the inter carrier interference and inter block interference. In this paper, Tomlinson Harashima precoder and dirty paper coding techniques are considered to eliminate interference due to other signals in the system. In the existing paper, channel inversion and regularized channel inversion techniques, this can assist to cancel Inter Block Interference (IBI).