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Hybrid computing environment is making rapid progress in acceptance by SMEs, government agencies, universities and scientists. Such computing environment cannot only reduce management costs, but is pivotal to enabling next generation of applications on unprecedented scales. Research and development efforts in hybrid computing environments are still at infancy. More tangible efforts are needed, if hybrid computing environments has to become primetime. Hybrid computing environments has potential to improve many application areas including scalable programming (such as HPC and multi-core), future networking and general application provisioning. The researchers not only need to overcome technological challenges, but also legal, economic, environmental, and standardization challenges.