Cloud Computing is a new technology which use the Internet and central remote servers in order to maintain data and applications. The aim of this paper is to describe about Case Based Reasoning (CBR) which is based on Multi Agent System (MAS) and the implementation in Cloud Computing Environment to assist the Cloud Service Provider (CSP) to deliver a number of services to the cloud users according to their needs. The Introduction Section gives an introduction about Cloud Computing, MAS and CBR Integration, and defines the characteristics and process cycle of CBR. The Second Section describes about the MAS-Based Cloud Computing. The Third Section describes about the CBR in Cloud Computing.