MIMO-OFDM technology is a combination of Multiple-Input Multiple-Output (MIMO) wireless technology with Orthogonal Frequency Division Multiplexing (OFDM) that has been recognized as one of the most promising techniques to support high data rate and high performance in different channel conditions. The authors have focused on developing the six symbol detection algorithm of WiMAX system for the MIMO-OFDM receiver. To find best signal detection technique for WiMAX system in MIMO-OFDM environment. MIMO-OFDM system gives BER that they required for next generation wireless system i.e. WiMAX and also gives high data rates that can be useful for many wireless systems.