Direct Sequence Code Division Multiple Access (DS-CDMA) system is well known wireless technology. This system suffers from MAI (Multiple Access Interference) caused by Direct Sequence users. Multi-User Detection schemes were introduced to detect the users' data in presence of MAI. Linear Multi-user Detectors and conventional Matched Filter (MF) are simulated using gold, PN and even kasami sequences as spreading codes in DS-CDMA system. In this paper odd kasami sequence is proposed. The Bit Error Rate (BER) performance of MMSE Detector provides better than Decorrelating detector and conventional Matched filter. Comparative Study shows that the proposed odd kasami sequence is better performed than gold, PN and even kasami sequences in linear Multi-user Detectors and conventional Matched Filter (MF).