CD tray automatically opens

I have a PIII machine running W2K SP4. It has a CD Reader in it. Each time I boot up the CD tray automatically opens. If the client closes it, it automatically opens several times during the day.
My first thought was a piece of software trying to install however all software is loaded from an administrative install. This is one of 60 machines with the same image. The other machines do not have this problem.
Where do I look for settings.