How critical is network security for your business?
To protect from general internet threats most firewall will do the job
watch guard, Fortinet, & ASA 55.. are in Unified Solution category (or All -in -one Box).
while Cisco PIX will be plain vanilla firewall.
IF you are looking at just firewall functionality then go ahead and pick up PIX
But Firewalls are not enough in current scenario.
watch guard and fortinet has lot of features , like AV, Anti-spam, Url filter, IDS etc.. Probably Fortinet will be slightly better than watchguard
Cisco ASA5500 is a new product in the market and don't have much info on it.
If you have serious security concerns look at ISS Proventia M Series which an Unified Security solutions. The IPS they have is one of the Best in the market.
Also size the firewall for your requirement... PIX 525\535 looks like an overkill for 50 user network
rgds,