Move from site to regional role?

Please advise how shall I move from site role to regional role or shall I look elsewhere?

Two years old I move from a site role(include a bit of regional exposure) in my previous company to a company which global presence. I was at first performing a regional role till there had been some politics issue with site that I was required to move to a site role. I was totally frustrated. But time and time I am trying to get myself back into a regional role but to no avail.

Shall I hold on or move on?