Save File to Application

I have a VB.Net application that stores some project files against projects in the database. I am having difficulty getting users to use the app to add the files.

I would like to be able to create an add in to explorer that would create a new drive to save to from any application. When the users selects the drive it would open an application allowing them to choose the project to save the file against and then save the file to the database.

Is this possible?

I could create a new menu add in to office that would call up my application but this obviously would not apply to Adobe Acrobat, Photoshop or other apps that are used in my organisation.