spybot program "search and destroy"

This is a cut and paste answer. Your problem is a known bug in Spybot. And your work around is the correct way to temporarily deal with the problem.
but there is also a fix for the problem....... see the cut and paste.

hy does the scan hang during detection of C2.lop?link FAQ #022

The exact reason isn't yet known, as this error seems to be sporadic and only on a few machines, but there's a simple way around it. Start Spybot-S&D in advanced mode, open the Excludes section, and select C2.lop for exclusion of the scan (tick the checkbox in front of the C2.lop entry). This will avoid scan of C2.lop until a bugfix comes out (soon).

Update (May 7th): the reason for this hang is a corrupted file, located either in the Temp or in the Application Data folder. There is an update available that can deal with this problem; if you check for updates, be sure to download the one named File check library. Or download the manual updater if you don't want to use the update function.

http://security.kolla.de/index.php?lang=en&page=knowledgebase/faq/faq022

As mentioned above you should check for updates as they do have a patch for this hang. However I have one workstation with Win2k SP4 that still needs the exclude on the C2.lop for it to run. You will notice, there are two mentioned. I only checked the first and the program ran correctly. The reason I did not check the second is because I knew that computer had Had A Browser Hijacker from running Adaware.
I half way think like you that the computer has the C2.lop and it won't allow the program to check it. I would like to hear from SpyBOT on this.
Apparently the C2.lop gives you an additional toolbar if you have it,check out this link: http://www.doxdesk.com/parasite/lop.html