vb.net error when launching exe

I am trying to run a Setup.exe file from within VB.net 2008. I have used the code below and get the error message: “Windows cannot find REBOOT=ReallySupprress…” then a second error comes up: “Could not execute external program. REBOOT=ReallySuppress”. I’ve even tried using Shell with the same error. Can anyone tell me why this is happening and what I can do to run this executable?

Code:
System.Diagnostics.Process.Start(“C:\Documents and Settings\User\Desktop\Setup.exe”)

–Tony–