Copying a desktop

If they are the only user on the workstation, and you did not have user profiles before, the default profile will turn into the Client for MS net. profile you want.
If not, you have two options,
1, not login to the domain, (kinda defeats the purpose though, doesn't it?)
2. copy the profile settings and configurations, and move them into the new windows\profiles\ folder that will be created.
For some of the programs, you may need to recreate the shortcuts, (the program is still installed) or place things back into the startup menu.
Good Luck,

You dont say your desktop OS?
If you have NT Workstation or Win2K Pro on the desktop then what you want to do is this
1) Log the user into the domain. (This creates their domain profile on the network. Logout (dont configure anything)
2) Log inas the local admin, local user, or domain admin (any one of the three will work).
3) Right Click My computer and choose the User Profiles tab.
4) Select the LOCAL users profile and click Copy To..
5) Browse to:
NT4 (or upgraded W2K)- C:\winnt\profiles\
Win2k Pro-
C:\Documents and Settings\
Click Ok a couple times.
6) Log-out
7) Log in as the domain user and Presto the domain profile is exactly the same as the local was.
8) Delete the local profile, so its never used again. Always have them use the domain profile.