Exchange 2000 Bounced message

We have a few domains that are hosted by register.com that when we try to send from our enviroment they get bounced back to us with a 4.4.7 error. I’ve talked to register.com their ISP our ISP and nobody can help me with this problem. They were able to recieve e-mails from us back in July but now they can’t anymore. We can recieve e-mails from them just fine. I didn’t make any changes on our Exchange server in many months. Any help on troubleshooting this error would be great. Thanks for your help.