The Service Pack installation routine will normally notify you if any running services or applications will interfere with the installation of the service pack. Since you are required to reboot for the installation to take effect, it's usually a good idea to shut down all running applications (like Exchange and SQL). In fact, if you will be installing the Exchange service pack immediately (or almostimmediately) after installing the Win2K service pack, I suggest the following: prior to installing the Win2K SP, stop the Exchange services and change the service startup type to Manual. This will effectively prevent Exchange from restarting after your reboot for the Win2K SP installation. You can then jump into the Exchange SP installationwithout having to shut down Exchange again. Before you perform the required reboot, change the Service startup type back to Automatic for all Exchange services. Exchange will then automatically restart (hopefully) upon reboot.
If I remember correctly, you must shut down ALL Exchange services to install the Exchange service pack