Is the front USB Port on a Fly Lead from the M'Board?
Does this happen if you use a Back Port with the same devices?
What can happen is that the Lead from the front USB Ports to M'Board acts like an aerial and gathers stray Electro Magnetic Signals. Not a uncommon thing to happen particularly if you are in a dirty EM Environment. The answer is to use a Powered USB Hub connected to a Back USB Port/Socket that is one directly connected to the M'Board not through a Fly Lead. While you may be able to move the Fly Lead around inside the case to stop this depending on what the actual computer is and what Plug In Cards are involved you may be successful but you are just as likely to be unsuccessful or even make matters worse. It's the nature of EM Signals unfortantly but if you really want to try something I would suggest starting with a Good Brand Name Power Supply like one of Antec's True Power units and then work your way around the insides of the system from there. It may work but as I said previously things could get much worse as well. Though if you just changed the Power Supply it's not going to hurt anything except your Hip Pocket as the Antec Power Supplies are excellent and filter out everything. I've even seen one sacrifice itself and save the computer when a tree fell on the power lines and brought the Overhead Transmission lines at 11KV into direct contact with the Distribution side of the grid here at 240V. Only thing in the entire neighborhood that worked again after that incident. That incident sold me on those Power Supplies and they are all I’ve ever used since.