Coordinates

2 cents if i may, not worth much:
your question sure makes me wonder what context you are asking it in...to try to answer i don't know of any way to get that info from windows explorer by looking at the screen. Graphics and cad programs (Accessories/Paint) display a set of coordinates. but of course it's all relative and that is not what you mean i bet.
i bet you need mouse software or screen capture software to do this...or be a windows programmer. you might cheat there and try vba in excel or something. create a windows with the cursor co-ords in there. that would not be easy without help from programmers here. who would surely want to know how/why you want this so to tailor applet accordingly...
the info has to be there doesn't it, because windows obviously knows. so my guess is that you could get at this with a visual basic routine or other language having windows api calls...it ought to be calculable also, given screen and mouse resolution...this strikes me as something that might be included in mouse software like mouseware or intellipoint...check for downloads from mouse manufactuer websites. kensington, logitech and maybe go to downloads.com or tucows.com and look for screen capture type utilities...