Crash after security patches

I applied the recent MS security patches. Unknown to me, the patch process ate up all of the 50MB or so that was available on C: drive and took disk to 0 bites left. The patch process, however, did not complain, and normally completed and started the process of rebooting the PC. Upon reboot, the machine will not respond to the keyboard when the “press Cntl,ALt Del” comes up. At a complete loss, I rebooted to DOS, deleted a bunch of unneeded files to make space on the disk, and ultimately tried to reinstall NT. It still will not respond to the key combo to start the system. Anybody got a remedy???
Help!