Exchange 2000 MSEXchangeMTA errors

My exchange 2000 event log keeps filling up with messages regarding MSExchangeMTA and MSExchangeIS like the following:
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0 messages are waiting to be transferred out to the Microsoft Exchange MTA (sent) from gateway /o=EssentialMarkets/ou=First Administrative Group/cn=Configuration/cn=Connections/cn=SMTP (EXCHANGE)/cn={49FA12E6-DD8D-446C-BFFF-F422404E6AB5}.
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The wakeup send thread on database “First Storage Group\Mailbox Store (EXCHANGE)” will retry submitting the message in 5000 msec.
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Any idea what is going on?