Hugecrush.com

A friend of mine got a spam email from this site and went to it thinking someone had a crush on him (poor sucker!) when he logged into the site with his email address he was required to click on a link to install a file which he did called open.exe.

I looked at his machine and went into the registry and deleted all the instances of http://www.secret-crush.com/search/ which change his main home page of http://www.msn.com/ and then rebooting this page still comes up.

My question is how can I clean this out completely? Also, Is this all the open.exe does? Is there something else it does beside change the homepage? Also, does anyone know any history behind this web site?