missing chimouse.vxd file

Each time I start up I get the following message.

System.ini file refers to a file chimouse.vxd that no longer exists. Try uninstalling with its uninstall program of setup program. Or try reinstaling it to replace the missing file.

press key to continue.

I have deleted as much as I can find of this file, but still get the same message.

How do I get rid of this message?