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Preventing execution

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I have been given to understand that there is a method of listing specific executables within the os (the rumor held that it was the msdos.sys file) to prevent that specific files execution. Has anyone heard of this - is it possible. This would be very handy in my particular environment? I have searched MSDN unsuccessfully.

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by rbresee

I didn't think msdos.sys could do it. Unfortunately, what i am looking for is the ability to prevent specific executables, not limit the system to a given set of executables.

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