Program opening slow over network

I have a machine on our network that takes forever to open up a word doc. from another machine on the same network, have tried ping – ttl is 128 other machines dont have same problem, if I open a word doc from the Hdd it opens immediately. The card is running in full duplex mode, could this be a missing or corrupted file? which file would it be? I have not hung arround to wait and see if the doc opens when getting it over the network.