serial port communication in vb.net

Hi,

I am working on a project to write code to control an RTX robot arm by communicating through the serial port. I would like to write the serial port communication in vb.net, the GUI in C#.net and the low level functions to control the arm in C. Is it possible for me to approach the project in this way?

I have already learnt C and am going to start learning some vb.net and C#

Thanks for your help

Enoch