i got a few hits from mskb at support.microsoft.com '10006 DCOM'
so we do need mre data but here i found this also
PRB: Application Center 2000 Service Pack 1 Is Not Supported on Windows 2000 Service Pack 4
Article ID : 827803
Last Review : November 26, 2003
Revision : 5.0
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SYMPTOMS
CAUSE
RESOLUTION
STATUS
SYMPTOMS
After you install Microsoft Windows 2000 Service Pack 4 (SP4) on a computer that is running Microsoft Application Center 2000 Service Pack 1 (SP1), some features and administrative tasks (such as setting members offline or online) may stop responding.
Additionally, the following error may appear in the system event log:
Event ID: 10006
Source: DCOM
Event Type: Error
Description: DCOM got error "%%2147749891" from the computer XXX.XXX.XXX.XXX when attempting to activate the server: {1EE00BE5-A7F3-4ED1-952F-B21256F53BF5}
CAUSE
This problem occurs because Windows 2000 SP4 contains security updates that are included from Microsoft Windows Server 2003 that are not supported by the Application Center Event Provider in Application Center 2000 SP1. Therefore, Windows 2000 SP4 is not compatible with and is not supported with Application Center 2000 SP1.
RESOLUTION
To resolve this problem, install Microsoft Application Center 2000 Service Pack 2 (SP2). This SP updates the Application Center Event Provider to a decoupled provider, and the change works successfully with the changes in Windows Server 2003. The provider changes are required for Windows 2000 SP4.
To obtain Application Center 2000 SP2, visit the following Microsoft Web site:
http://www.microsoft.com/applicationcenter/downloads/
STATUS
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section of this article. This problem was first corrected in Application Center 2000 Service Pack 2.
APPLIES TO
? Microsoft Application Center 2000 SP1