What to consider when installing win2000

We are installing Win2000 on all out machines in our corporate network. Have been running Win95 up til now an we are currently creating ghostimages for every machine type that we have. Just wondering if anyone has any suggestions on which SP:s and security updates an so on that should be used, and which ones that should be avoided. We are also upgrading to Office2000 and IE5.5. We are also upgrading our servers to Novell 5.
Thx!