Anti-Spyware for the Enterprise?

Hello, I know that the enterprise anti-spyware space is still in it’s infancy…but our management wants a solution NOW, and I’ve been tasked with reviewing several contenders.
Currently we use Spybot, which is OK for the price (free) but is not enterprise. We need something that can be centrally managed (for installing clients and updating definitions).
We’re going to evaluate CA eTrust PestPatrol (even though CA software sucks PestPatrol was actually pretty decent). Also SunBelt CounterSpy Enterprise and Webroot’s SpySweeper Enterprise.
Anyone have any comments/ suggestions?