Concerning USB access block

I have recently acquired a USB access block on both my laptop and my desktop computer. Both show in Device Manager the yellow triangles on all USB drivers, and inquiry says drivers are OK but hardware cannot be found. Updating drivers does not cure nor does removal and auto-install or reboot. I also note that all restore points do not work either, suggesting that this and the commonality of onset is a virus or worm I have acquired. Has anybody had experience with this and a cure, short of wipe and redo?