Try reposting this in the 'Q&A' forum. The 'Discussion' forum is for matters of general discussion, not specific problems in search of a solution. The 'Water Cooler' is for non-technical discussions. You can submit a question to 'Q&A' here:
https://www.techrepublic.com/forum/questions/post?tag=mantle_skin;content
There are TR members who specifically seek out problems in need of a solution. Although there is some overlap between the forums, you'll find more of those members in 'Q&A' than in 'Discussions' or 'Water Cooler'.
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[b]However in the mean time[/b] What changes where made to your Desktop just before this stopped working?
Remember that Hot Patches supplied on Microsoft Tuesday are a change.
I'm also supposing that when you say [i]I don't want to do a reboot on my PC, saving that as a last option.[/i] Actually means you do not want to reload the system as it should have been shut down to remove the WiFi Card. If you pulled it with the system running it's not going to do the card or the computer much good.
Here I would say that there is a Security Issue involved with either a Hot Fix or some new software that has been installed and rolling back to an earlier Restore Point should fix the issue if the OS is not to badly messed up at least. ;)
Col