After attempting to do an upgrade installation of Vista over XP Pro, I ended up doing a clean installation. For the first 5 days, I was able to load progams and otherwise use my CD/DVD drive normally. I attempted to install a program from my USB drive that ended up not installing because of incompatability with Vista. The following morning, my CD/DVD drive was not being recognized. I got an error message stating ‘Windows cannot load the device driver for this hardware. The driver may be corrupted or missing. (Code 39).’ I uninstalled the driver and then restarted the computer, with the same result. I then did a system restore, to the last time the CD/DVD drive was working, but still it is not being recognized by the computer. The drive is an AOpen DVD 1648BKH, which I purchased in 1993. The AOpen website lists it as an end of life product, which I assume means they are no longer supporting it. I cannot locate any CD with the drivers, and therefore I am not sure how to fix this, other than to replace the drive. However, I’m not sure whether the problem is actually with the drivers or something else happened to Vista. I was told by a tech. support person at one of the CompUSA stores that this is a known problem with Vista….that after attempting to install incompatable programs, you can have driver issues with devices in the computer. Does anyone have any thoughts about a fix?