What are the key challenges for a Custodian?

With economic recovery sailing in slow but steady pace, Custody business is more likely to have a rush of adrenalin primarily due to two major reasons:
1) As an effect of economic recovery, the value of world’s Asset is going to surge
2) New areas of investment and new product lines which will emerge to serve the new wealth management clients will create a new line of challenge for Custodians.

What are today’s key challenges for a custodian?