Did your client install any software prior to these events occuring? If so, that is most likely your suspect. Boot into safe mode and remove it.
Now, I have, unfortunately, seen something like this before. I believe it was a virus/trojan. Not sure. I had gotten, and please don't laugh, a file from kazaa (*sigh* I know, bad boy!) upon executing it, both my antivirus and firewall programs were disabled and my cpu was taken to 100%. Once I found the service that was using 100% usage, I attempted to just end it, well, it came right back, using IExplorer.exe to execute it. I also located the files behind it, but obviously couldn't delete them due to them being in use. So, what ya have to do is rename temporarily your iexplorer.exe to something else. End the process, bingo it can't restart. Then just delete the bad files. Now you can rename your iexplorer.exe back to normal and reboot. All worked fine after that. During this whole situation, I did get the 'serious error' and couldn't browse anything. Hope this helps.
Woody