Can I have two domains on one server?

Hello all!

I’m new to setting up some network at a school, so I wonder if anybody can help me?

At my workplace we have just one server and a domain (HKU).. Now the school is creating a special course, and the course should have generated a whole special start-menu, and a few special programs..

Is is possible to create a second domain (SPIL), or is there an easier way to let the new course only have access to a few programs?

Kind regards,
Steffen