When you create the user, on the profiles tab, in the Home directory designation, choose the drive letter you want to map the home directory to, and then put the path in the path field. You can use the "%username%" variable (i.e., \\servername\home\%username%) in the path, and the folder will be automatically created with their user ID as the name and they will automatically have Full Control of the folder. If you are using some sort of template user that you then copy to create new users, you can add this to that user also and it will always be applied, along with all the other template settings, to each new user.
Hope this helps!