EVENT ID’s 1053,1054,40960,40961

Can anyone give me some insight. I keep getting Event Id’s errors 1053 & 1054. I also get event id error codes 40960 & 40961. I have a small network with 3 sites. ONly one site with the domain controller is having issues loosing conections. Mainly with outlook. Its not on ever machine at this 1 site. Any insight would help. Thanks!