How to configure Loopback Adapter to communicate with Real Network ?

Hi,

How to configure Loopback adapter to communicate with the real networks. i am having one adapter on my pc which is connected to my LAN. i have created a ms loopback adapter.

My PC IP address is 10.45.1.2/24
Gateway address is 10.45.1.1

i tried to use my pc ip address as my loopback adapter’s Gateway address, But it’s NOT working. can anyone help me plz.