How TO configure MDaemon with isa server 2004

Hi, I have problem with MDaemon mail server , run with ISA server 2004
Hi , I have problem woth MDaemon mail server that i setup it in the computer with ISA server 2004 under windows 2003. the problem is i cannot send to email out side .please help me.
how to properly configure isa server2004 with MDeamon.

irshadali_ali@hotmail.com
irshadbaba2002@yahoo.com
Thanks