Management Interface for desktop management

Greeting, question to the IT professionals who have experience with network/systems management across enterprises.

Which management interface you would prefer to use, to manage enterprise infrastructure software for managing desktops in a distributed enterprise with large amount of desktops, including image management, support, and protection.

Options:

1. MMC snap in

2. Web GUI

3. Dedicated GUI

4. Combination of the above? please specify which you would prefer

Why would you choose one vs another?