Moving ARCserve 6.5 DB – Any gotcha’s?

I currently have ARCserve 6.5 installed on the C drive (Boot partition) of my NT4 (SP6) server. I’m receiving “getting FULL” type messages from the server primarily due to the size of the ARCserve DB. I would like to relocate the entire app/service or just the database to another drive/partition. You can understand my anxiety in doing so.
Has anybody successfully done this? Were there any hangup’s? Did you run into any glitches? LOOKING FOR EXPERIENCED ADVICE