SpyWare Removal

My Internet Explorer is set to open as a blank page,but everytime internet explorer opens a page comes up http://www.topsecuritysite.net/(Security Center) and everytime my computer boots up the system32 folder appears, i know it is a spyware, i uses Ad-aware , Cccleaner , Windows Defender, Live One Care,all update w/ definition but to no avail
screenshot
[IMG]http://i6.tinypic.com/14949wm.jpg[/IMG]
Using Windows Xp Sp2
regards to all