System32 Directory Pops Up Logging In

When logging into our Citrix server, an explorer like screen comes up titled system32. This happens logging into the server and at the client workstation. We are thinking that this comes up because of an application looking for and not finding a file in the system32 directory. There is an application that we had a hard time installing that was successfully installed right around the time the error started. What is the best way of determining the cause of this or resolving the issue?