runtime error 429 on vista

Did you do a 'run as administrator' when you installed the application? If not, I would do a reinstall whilst choosing 'run as administrator'. Most likely some critical dll did not get registered properly.

To patch it manually:
Look in your application logs to see if you can spot the offending dll.

Not the most elegant method, but I would take a look at the installer directory, see what dlls are part of the app, then attempt to manually register each one. You cannot register a dll twice, and most simple apps just use two or three dlls.

http://www.ehow.com/how_2056399_manually-register-dll-windows-vista.html