2nd boot from cd hangs up!

I set the bios to boot from cd and booted up to install w2k. It boots up ok and starts the install. When the w2k install setup restarts the computer the boot from cd hangs up. The reboot just freezes on “boot from cd, hit any key” I reset the bios to not boot from the cd and it still hangs. Do I have a Bios problem or a cd rom problem? Or am I missing the boat here? What advice can you give to me. I need some ideas on what to try. Please walk me thru any ideas you may have. Thanks.