Irregular PC lockups

I have recently upgraded my motherboard and since I have had this board my PC keeps locking up and does not run certain programs, which work fine on my old board.
The basic problems are, when I try to access my scanner software, the PC will lock upand I have to restart. When I try to run certain games, the intro plays fine, but then when the main game loads, again the system locks up. Also my printer prints half a page and then finishes the print job.
Is this a problem with the board or some other aspect of my system. I am willing to enter into discussions with anyone who can help me with this problem.